I will be out of town for Christmas Eve and Christmas day. I have three large dogs Two Alaskan Malamute & Husky mixed with Aussie. They have been around cats I have two cats of my own. I personally would not trust Mel around cats alone. Those who have experience with large dogs or my personal breeds feel free to reach out. They are all house trained and on a schedule. They do have crates as well if that helps! I know it is the holiday so I am very flexible with the arrangements of there stay.